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A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome

Many genetic mutations have been identified as monogenic causes of nephrotic syndrome (NS), but important knowledge gaps exist in the roles of these genes in kidney cell biology and renal diseases. More animal models are needed to assess the functions of these genes in vivo, and to determine how the...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Fu, Yulong, Zhu, Jun-yi, Richman, Adam, Zhao, Zhanzheng, Zhang, Fujian, Ray, Patricio E., Han, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074792/
https://ncbi.nlm.nih.gov/pubmed/28164240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw428
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