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The HOOK region of voltage-gated Ca(2+) channel β subunits senses and transmits PIP(2) signals to the gate
The β subunit of voltage-gated Ca(2+) (Ca(V)) channels plays an important role in regulating gating of the α1 pore-forming subunit and its regulation by phosphatidylinositol 4,5-bisphosphate (PIP(2)). Subcellular localization of the Ca(V) β subunit is critical for this effect; N-terminal–dependent m...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299622/ https://ncbi.nlm.nih.gov/pubmed/28087621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611677 |
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