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Adipose tissue CLK2 promotes energy expenditure during high fat diet intermittent fasting

A promising approach to treating obesity is to increase diet-induced thermogenesis in brown adipose tissue (BAT), but the regulation of this process remains unclear. Here, we find that CDC-like kinase 2 (CLK2) is expressed in BAT and upregulated upon refeeding. Mice lacking CLK2 in adipose tissue ex...

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Bibliografische gegevens
Gepubliceerd in:Cell Metab
Hoofdauteurs: Hatting, Maximilian, Rines, Amy K., Luo, Chi, Tabata, Mitsuhisa, Sharabi, Kfir, Hall, Jessica A., Verdeguer, Francisco, Trautwein, Christian, Puigserver, Pere
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299049/
https://ncbi.nlm.nih.gov/pubmed/28089567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.12.007
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