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Targeting hepatic glucose output in the treatment of type 2 diabetes

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis resulting in hyperglycemia. Although current diabetes treatments have exhibited some success in lowering blood glucose, their effect is not always sustained and their use may be associated with undesirable side eff...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Drug Discov
Hoofdauteurs: Rines, Amy K., Sharabi, Kfir, Tavares, Clint D. J., Puigserver, Pere
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751421/
https://ncbi.nlm.nih.gov/pubmed/27516169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.151
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