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Targeting hepatic glucose output in the treatment of type 2 diabetes

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis resulting in hyperglycemia. Although current diabetes treatments have exhibited some success in lowering blood glucose, their effect is not always sustained and their use may be associated with undesirable side eff...

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Bibliografiske detaljer
Udgivet i:Nat Rev Drug Discov
Main Authors: Rines, Amy K., Sharabi, Kfir, Tavares, Clint D. J., Puigserver, Pere
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751421/
https://ncbi.nlm.nih.gov/pubmed/27516169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.151
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