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Targeting hepatic glucose output in the treatment of type 2 diabetes

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis resulting in hyperglycemia. Although current diabetes treatments have exhibited some success in lowering blood glucose, their effect is not always sustained and their use may be associated with undesirable side eff...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Rines, Amy K., Sharabi, Kfir, Tavares, Clint D. J., Puigserver, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751421/
https://ncbi.nlm.nih.gov/pubmed/27516169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.151
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