Mutations in p53 as potential molecular markers for human breast cancer.
Based on the high incidence of loss of heterozygosity for loci on chromosome 17p in the vicinity of the p53 locus in human breast tumors, we investigated the frequency and effects of mutations in the p53 tumor suppressor gene in mammary neoplasia. We examined the p53 gene in 20 breast cancer cell li...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1961733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10657 |
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