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Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.

Overexpression of the p53 protein, resulting from gene mutations that increase protein stability, has been detected in greater than 25% of primary human breast cancers. In addition, approximately 10% of breast cancer patients have circulating antibodies to the p53 protein. In this study, the anti-p5...

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Detalhes bibliográficos
Main Authors: Davidoff, A M, Iglehart, J D, Marks, J R
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48883/
https://ncbi.nlm.nih.gov/pubmed/1373500
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