Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus

Generally, the antagonism between host restriction factors and viral countermeasures decides on cellular permissiveness or resistance to virus infection. Human cytomegalovirus (HCMV) has evolved an additional level of self-imposed restriction by the viral tegument protein pp150. Depending on a cycli...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Weisbach, Henry, Schablowsky, Christoph, Vetter, Barbara, Gruska, Iris, Hagemeier, Christian, Wiebusch, Lüder
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298330/
https://ncbi.nlm.nih.gov/pubmed/28129404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006193
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