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Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus

Generally, the antagonism between host restriction factors and viral countermeasures decides on cellular permissiveness or resistance to virus infection. Human cytomegalovirus (HCMV) has evolved an additional level of self-imposed restriction by the viral tegument protein pp150. Depending on a cycli...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Weisbach, Henry, Schablowsky, Christoph, Vetter, Barbara, Gruska, Iris, Hagemeier, Christian, Wiebusch, Lüder
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298330/
https://ncbi.nlm.nih.gov/pubmed/28129404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006193
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