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The Latency-Associated UL138 Gene Product of Human Cytomegalovirus Sensitizes Cells to Tumor Necrosis Factor Alpha (TNF-α) Signaling by Upregulating TNF-α Receptor 1 Cell Surface Expression

Many viruses antagonize tumor necrosis factor alpha (TNF-α) signaling in order to counteract its antiviral properties. One way viruses achieve this goal is to reduce TNF-α receptor 1 (TNFR1) on the surface of infected cells. Such a mechanism is also employed by human cytomegalovirus (HCMV), as recen...

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מידע ביבליוגרפי
Main Authors: Montag, Christina, Wagner, Jutta Annabella, Gruska, Iris, Vetter, Barbara, Wiebusch, Lüder, Hagemeier, Christian
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194957/
https://ncbi.nlm.nih.gov/pubmed/21880774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05028-11
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