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A natural, single-residue substitution yields a less active peptaibiotic: the structure of bergofungin A at atomic resolution

Bergofungin is a peptide antibiotic that is produced by the ascomycetous fungus Emericellopsis donezkii HKI 0059 and belongs to peptaibol subfamily 2. The crystal structure of bergofungin A has been determined and refined to 0.84 Å resolution. This is the second crystal structure of a natural 15-res...

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Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Gessmann, Renate, Axford, Danny, Brückner, Hans, Berg, Albrecht, Petratos, Kyriacos
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297930/
https://ncbi.nlm.nih.gov/pubmed/28177320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17001236
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