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Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells

Talin is a focal adhesion protein that activates integrins and recruits other focal adhesion proteins. Talin regulates the interactions between integrins and the extracellular matrix, which are critical for endothelial cells during angiogenesis. In this study, we successfully synthesized a novel tal...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Lim, I-Rang, Joo, Hyung Joon, Jeong, Minseon, Kim, Jong-Ho, Choi, Seung-Cheol, Kim, Chungho, Jung, Jong-Wha, Hong, Soon Jun
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297850/
https://ncbi.nlm.nih.gov/pubmed/28117756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010221
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