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Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells

Talin is a focal adhesion protein that activates integrins and recruits other focal adhesion proteins. Talin regulates the interactions between integrins and the extracellular matrix, which are critical for endothelial cells during angiogenesis. In this study, we successfully synthesized a novel tal...

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Publicat a:Int J Mol Sci
Autors principals: Lim, I-Rang, Joo, Hyung Joon, Jeong, Minseon, Kim, Jong-Ho, Choi, Seung-Cheol, Kim, Chungho, Jung, Jong-Wha, Hong, Soon Jun
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297850/
https://ncbi.nlm.nih.gov/pubmed/28117756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010221
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