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Osteocyte Alterations Induce Osteoclastogenesis in an In Vitro Model of Gaucher Disease
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid glucocerebroside in the lysosomes of cells, mainly in the monocyte/macrophage line...
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| Publicado en: | Int J Mol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5297746/ https://ncbi.nlm.nih.gov/pubmed/28098793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010112 |
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