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Pathogenesis of Bone Alterations in Gaucher Disease: The Role of Immune System

Gaucher, the most prevalent lysosomal disorder, is an autosomal recessive inherited disorder due to a deficiency of glucocerebrosidase. Glucocerebrosidase deficiency leads to the accumulation of glucosylceramide primarily in cells of mononuclear-macrophage lineage. Clinical alterations are visceral,...

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Détails bibliographiques
Publié dans:J Immunol Res
Auteurs principaux: Mucci, Juan Marcos, Rozenfeld, Paula
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433682/
https://ncbi.nlm.nih.gov/pubmed/26064996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/192761
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