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A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway

Accumulation of misfolded/unfolded proteins in the endoplasmic reticulum (ER) leads to the activation of three branches (Protein kinase (RNA)-like endoplasmic reticulum kinase [PERK], Inositol requiring protein 1 [IRE-1] and Activating trascription factor 6 [ATF6], respectively) of unfolded protein...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Márton, Margita, Kurucz, Anita, Lizák, Beáta, Margittai, Éva, Bánhegyi, Gábor, Kapuy, Orsolya
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297693/
https://ncbi.nlm.nih.gov/pubmed/28067773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010058
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