Tumor LINE-1 Methylation Level in Association with Survival of Patients with Stage II Colon Cancer

Genome-wide DNA hypomethylation is associated with a worse prognosis in early-stage colorectal cancer. To measure genome-wide DNA methylation levels, long interspersed nucleotide element (LINE-1) repeats are used as a surrogate marker. Cohort studies on the clinical impact of genome-wide DNA methyla...

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Publicado en:Int J Mol Sci
Autores principales: Swets, Marloes, Zaalberg, Anniek, Boot, Arnoud, van Wezel, Tom, Frouws, Martine A., Bastiaannet, Esther, Gelderblom, Hans, van de Velde, Cornelis J. H., Kuppen, Peter J. K.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297671/
https://ncbi.nlm.nih.gov/pubmed/28035987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010036
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