Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues

Mice harbouring a dentin matrix protein 1 (Dmp1) promoter-driven human diphtheria toxin (DT) receptor (HDTR) transgene (Tg) have recently been used to attain targeted ablation of osteocytes by diphtheria toxin (DT) treatment in order to define osteocyte function. Use of these Tg mice has asserted me...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Al-Jazzar, Ahmed, Javaheri, Behzad, Prideaux, Matt, Boyde, Alan, Scudamore, Cheryl L., Cherifi, Chahrazad, Hay, Eric, Hopkinson, Mark, Boyd, Michael, Cohen-Solal, Martine, Farquharson, Colin, Pitsillides, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297664/
https://ncbi.nlm.nih.gov/pubmed/28035954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010029
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