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Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis

The ability to suppress host macrophage apoptosis is essential for M. tuberculosis (Mtb) to replicate intracellularly while protecting it from antibiotic treatment. We recently described that Mtb infection upregulated expression of the host phosphatase PPM1A, which impairs the antibacterial response...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Schaaf, Kaitlyn, Smith, Samuel R., Duverger, Alexandra, Wagner, Frederic, Wolschendorf, Frank, Westfall, Andrew O., Kutsch, Olaf, Sun, Jim
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296758/
https://ncbi.nlm.nih.gov/pubmed/28176854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42101
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