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Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis
The ability to suppress host macrophage apoptosis is essential for M. tuberculosis (Mtb) to replicate intracellularly while protecting it from antibiotic treatment. We recently described that Mtb infection upregulated expression of the host phosphatase PPM1A, which impairs the antibacterial response...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296758/ https://ncbi.nlm.nih.gov/pubmed/28176854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42101 |
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