Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

BACKGROUND/OBJECTIVES: Central adiposity measures such as waist circumference (WC) and waist-to-hip ratio (WHR) are associated with cardiometabolic disorders independently of BMI and are gaining clinically utility. Several studies report genetic variants associated with central adiposity, but most u...

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Veröffentlicht in:Int J Obes (Lond)
Hauptverfasser: Yoneyama, Sachiko, Yao, Jie, Guo, Xiuqing, Fernandez-Rhodes, Lindsay, Lim, Unhee, Boston, Jonathan, Buzková, Petra, Carlson, Christopher S., Cheng, Iona, Cochran, Barbara, Cooper, Richard, Ehret, Georg, Fornage, Myriam, Gong, Jian, Gross, Myron, Gu, C. Charles, Haessler, Jeff, Haiman, Christopher A., Henderson, Brian, Hindorff, Lucia A., Houston, Denise, Irvin, Marguerite R., Jackson, Rebecca, Kuller, Lew, Leppert, Mark, Lewis, Cora E., Li, Rongling, Le Marchand, Loic, Matise, Tara C., Nguyen, Khanh-Dung H., Chakravarti, Aravinda, Pankow, James S., Pankratz, Nathan, Pooler, Loreall, Ritchie, Marylyn D., Bien, Stephanie A., Wassel, Christina L., Chen, Yii-Der I., Taylor, Kent D., Allison, Matthew, Rotter, Jerome I., Schreiner, Pamela J., Schumacher, Fredrick, Wilkens, Lynne, Boerwinkle, Eric, Kooperberg, Charles, Peters, Ulrike, Buyske, Steven, Graff, Mariaelisa, North, Kari E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296276/
https://ncbi.nlm.nih.gov/pubmed/27867202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2016.207
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