A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study

Genetic variants in intron 1 of the fat mass– and obesity-associated (FTO) gene have been consistently associated with body mass index (BMI) in Europeans. However, follow-up studies in African Americans (AA) have shown no support for some of the most consistently BMI–associated FTO index single nucl...

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Auteurs principaux: Peters, Ulrike, North, Kari E., Sethupathy, Praveen, Buyske, Steve, Haessler, Jeff, Jiao, Shuo, Fesinmeyer, Megan D., Jackson, Rebecca D., Kuller, Lew H., Rajkovic, Aleksandar, Lim, Unhee, Cheng, Iona, Schumacher, Fred, Wilkens, Lynne, Li, Rongling, Monda, Keri, Ehret, Georg, Nguyen, Khanh-Dung H., Cooper, Richard, Lewis, Cora E., Leppert, Mark, Irvin, Marguerite R., Gu, C. Charles, Houston, Denise, Buzkova, Petra, Ritchie, Marylyn, Matise, Tara C., Le Marchand, Loic, Hindorff, Lucia A., Crawford, Dana C., Haiman, Christopher A., Kooperberg, Charles
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547789/
https://ncbi.nlm.nih.gov/pubmed/23341774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003171
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