Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against different types of cancer. In order to translate these results to a preclinica...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lobos-González, Lorena, Silva, Verónica, Araya, Mariela, Restovic, Franko, Echenique, Javiera, Oliveira-Cruz, Luciana, Fitzpatrick, Christopher, Briones, Macarena, Villegas, Jaime, Villota, Claudio, Vidaurre, Soledad, Borgna, Vincenzo, Socias, Miguel, Valenzuela, Sebastián, Lopez, Constanza, Socias, Teresa, Varas, Manuel, Díaz, Jorge, Burzio, Luis O., Burzio, Verónica A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295434/
https://ncbi.nlm.nih.gov/pubmed/27507060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11110
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