Down-regulation of the Antisense Mitochondrial Non-coding RNAs (ncRNAs) Is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy

Hallmarks of cancer are fundamental principles involved in cancer progression. We propose an additional generalized hallmark of malignant transformation corresponding to the differential expression of a family of mitochondrial ncRNAs (ncmtRNAs) that comprises sense and antisense members, all of whic...

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Detalhes bibliográficos
Main Authors: Vidaurre, Soledad, Fitzpatrick, Christopher, Burzio, Verónica A., Briones, Macarena, Villota, Claudio, Villegas, Jaime, Echenique, Javiera, Oliveira-Cruz, Luciana, Araya, Mariela, Borgna, Vincenzo, Socías, Teresa, Lopez, Constanza, Avila, Rodolfo, Burzio, Luis O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175353/
https://ncbi.nlm.nih.gov/pubmed/25100722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558841
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