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Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

We reported that knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptotic death of several human tumor cell lines, but not normal cells, suggesting this approach for selective therapy against different types of cancer. In order to translate these results to a preclinica...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Lobos-González, Lorena, Silva, Verónica, Araya, Mariela, Restovic, Franko, Echenique, Javiera, Oliveira-Cruz, Luciana, Fitzpatrick, Christopher, Briones, Macarena, Villegas, Jaime, Villota, Claudio, Vidaurre, Soledad, Borgna, Vincenzo, Socias, Miguel, Valenzuela, Sebastián, Lopez, Constanza, Socias, Teresa, Varas, Manuel, Díaz, Jorge, Burzio, Luis O., Burzio, Verónica A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295434/
https://ncbi.nlm.nih.gov/pubmed/27507060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11110
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