Asymmetric Total Synthesis of Ieodomycin B

Ieodomycin B, which shows in vitro antimicrobial activity, was isolated from a marine Bacillus species. A novel asymmetric total synthetic approach to ieodomycin B using commercially available geraniol was achieved. The approach involves the generation of 1,3-trans-dihydroxyl at C-3 and C-5 position...

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Bibliografiske detaljer
Udgivet i:Mar Drugs
Main Authors: Lin, Shuangjie, Zhang, Jianting, Zhang, Zhibin, Xu, Tianxiang, Huang, Shuangping, Wang, Xiaoji
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295237/
https://ncbi.nlm.nih.gov/pubmed/28106760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15010017
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