Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

BACKGROUND: Juvenile myelomonocytic leukaemia (JMML) and chronic myelomonocytic leukaemia (CMML) are myelodysplastic myeloproliferative (MDS/MPN) neoplasms with unfavourable prognosis and without effective chemotherapy treatment. Trabectedin is a DNA minor groove binder acting as a modulator of tran...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Romano, Michela, Della Porta, Matteo Giovanni, Gallì, Anna, Panini, Nicolò, Licandro, Simonetta Andrea, Bello, Ezia, Craparotta, Ilaria, Rosti, Vittorio, Bonetti, Elisa, Tancredi, Richard, Rossi, Marianna, Mannarino, Laura, Marchini, Sergio, Porcu, Luca, Galmarini, Carlos M, Zambelli, Alberto, Zecca, Marco, Locatelli, Franco, Cazzola, Mario, Biondi, Andrea, Rambaldi, Alessandro, Allavena, Paola, Erba, Eugenio, D'Incalci, Maurizio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Translational Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294481/
https://ncbi.nlm.nih.gov/pubmed/28072764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.424
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