Novel benzoxazole derivatives DCPAB and HPAB attenuate Th1 cell-mediated inflammation through T-bet suppression

Interferon-γ (IFN-γ), a critical inflammatory cytokine, is primarily produced by T helper 1 (Th1) cells and accelerates the pathogenesis of inflammatory colitis. Pharmacological suppression of IFN-γ production attenuates dysregulated inflammatory responses and may be beneficial for treating inflamma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oh, Yeon Ji, Kim, Darong, Oh, Sera, Jang, Eun Jung, Won, Hee Yeon, Jeong, Hana, Jeong, Mi Gyeong, Choo, Hea-Young Park, Hwang, Eun Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294415/
https://ncbi.nlm.nih.gov/pubmed/28169371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42144
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