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Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation

Chloroquine (CQ) and amodiaquine (AQ) have been used for treating or preventing malaria for decades, and their application has expanded into treating inflammatory disease in humans. CQ and AQ are applicable for controlling rheumatoid arthritis, but their molecular mechanisms of anti-inflammatory act...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Oh, Sera, Shin, Ji Hyun, Jang, Eun Jung, Won, Hee Yeon, Kim, Hyo Kyeong, Jeong, Mi-Gyeong, Kim, Kwang Soo, Hwang, Eun Sook
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505558/
https://ncbi.nlm.nih.gov/pubmed/27109480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.04.105
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