Leucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways

Glucocorticoids (GCs) are negative muscle protein regulators that contribute to the whole-body catabolic state during stress. Mammalian target of rapamycin (mTOR)-signalling pathway, which acts as a central regulator of protein metabolism, can be activated by branched-chain amino acids (BCAA). In th...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Wang, Xiao J., Yang, Xin, Wang, Ru X., Jiao, Hong C., Zhao, Jing P., Song, Zhi G., Lin, Hai
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2016
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293580/
https://ncbi.nlm.nih.gov/pubmed/27129299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160096
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