Caricamento...
Allostery and Hysteresis are coupled in human UDP-glucose dehydrogenase
Human UDP-glucose dehydrogenase (hUGDH) is regulated by an atypical allosteric mechanism in which the feedback inhibitor UDP-xylose (UDP-Xyl) competes with substrate for the active site. Binding of UDP-Xyl triggers the T131-Loop/α6 allosteric switch, which converts the hexameric structure of hUGDH i...
Salvato in:
| Pubblicato in: | Biochemistry |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293408/ https://ncbi.nlm.nih.gov/pubmed/27966912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01044 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|