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Structural Basis of Cooperativity in Human UDP-Glucose Dehydrogenase
BACKGROUND: UDP-glucose dehydrogenase (UGDH) is the sole enzyme that catalyzes the conversion of UDP-glucose to UDP-glucuronic acid. The product is used in xenobiotic glucuronidation in hepatocytes and in the production of proteoglycans that are involved in promoting normal cellular growth and migra...
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Glavni autori: | , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2011
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184952/ https://ncbi.nlm.nih.gov/pubmed/21984906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025226 |
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