Structural Basis of Cooperativity in Human UDP-Glucose Dehydrogenase

BACKGROUND: UDP-glucose dehydrogenase (UGDH) is the sole enzyme that catalyzes the conversion of UDP-glucose to UDP-glucuronic acid. The product is used in xenobiotic glucuronidation in hepatocytes and in the production of proteoglycans that are involved in promoting normal cellular growth and migra...

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Detalhes bibliográficos
Main Authors: Rajakannan, Venkatachalam, Lee, Hui-Sun, Chong, Seon-Ha, Ryu, Han-Bong, Bae, Ji-Young, Whang, Eun-Young, Huh, Jae-Wan, Cho, Sung-Woo, Kang, Lin-Woo, Choe, Han, Robinson, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184952/
https://ncbi.nlm.nih.gov/pubmed/21984906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025226
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