Bacterial internalization is required to trigger NIK-dependent NF-κB activation in response to the bacterial type three secretion system

Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellular localization. We found that wildtype Yersinia ab...

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Vydáno v:PLoS One
Hlavní autoři: Duncan, Miles C., Herrera, Natalia G., Johnson, Kevin S., Engel, Joanne N., Auerbuch, Victoria
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293232/
https://ncbi.nlm.nih.gov/pubmed/28166267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171406
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