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Bacterial internalization is required to trigger NIK-dependent NF-κB activation in response to the bacterial type three secretion system
Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellular localization. We found that wildtype Yersinia ab...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293232/ https://ncbi.nlm.nih.gov/pubmed/28166267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171406 |
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