Transcriptional distinctions between normal and glioma-derived A2B5(+) progenitor cells identify a core set of genes dysregulated at all stages of gliomagenesis

Glial progenitor cells (GPCs) are a potential source of malignant gliomas. We used A2B5-based sorting to extract tumorigenic GPCs from human gliomas spanning WHO grades II-IV. mRNA profiling identified a cohort of genes that distinguished tumor-initiating progenitor cells (TPCs) from A2B5(+) GPCs is...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Auvergne, Romane M., Sim, Fraser J., Wang, Su, Chandler-Militello, Devin, Burch, Jaclyn, Fanek, Yazan Al, Davis, Danielle, Benraiss, Abdellatif, Walter, Kevin, Achanta, Pragathi, Johnson, Mahlon, Quinones-Hinojosa, Alfredo, Natesan, Sridaran, Ford, Heide, Goldman, Steven A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293199/
https://ncbi.nlm.nih.gov/pubmed/23727239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.035
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