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Fluorescent Ca(2+) indicators directly inhibit the Na,K-ATPase and disrupt cellular functions

Fluorescent Ca(2+) indicators have been essential for the analysis of Ca(2+) signaling events within the cells of the CNS. However, a systematic evaluation of their potential adverse effects is lacking. Here we show that chemical Ca(2+) indicators, but not a genetically encoded Ca(2+) indicator, pot...

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Vydáno v:Sci Signal
Hlavní autoři: Smith, Nathan A., Kress, Benjamin T., Lu, Yuan, Chandler-Militello, Devin, Benraiss, Abdellatif, Nedergaard, Maiken
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190706/
https://ncbi.nlm.nih.gov/pubmed/29382785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal2039
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