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Metabolic Enzyme Microarray Coupled with Miniaturized Cell-Culture Array Technology for High-Throughput Toxicity Screening

Due to poor drug candidate safety profiles that are often identified late in the drug development process, the clinical progression of new chemical entities to pharmaceuticals remains hindered, thus resulting in the high cost of drug discovery. To accelerate the identification of safer drug candidat...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Lee, Moo-Yeal, Dordick, Jonathan S., Clark, Douglas S.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293182/
https://ncbi.nlm.nih.gov/pubmed/20217581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-663-4_14
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