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Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses

The clinical progression of new chemical entities to pharmaceuticals remains hindered by the relatively slow pace of technology development in toxicology and clinical safety evaluation, particularly in vitro approaches, that can be used in the preclinical and early clinical phases of drug developmen...

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Autori principali: Lee, Moo-Yeal, Park, Chan Beum, Dordick, Jonathan S., Clark, Douglas S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC545843/
https://ncbi.nlm.nih.gov/pubmed/15657119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406755102
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