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Specific Binding of Cholesterol to C99 Domain of Amyloid Precursor Protein Depends Critically on Charge State of Protein
Recent NMR chemical shift measurements of the 99 residue C-terminal fragment of Amyloid Precursor Protein (APP-C99) in the presence of cholesterol provide evidence of binary complex formation between C99 and cholesterol in membrane mimetic environments. It has also been observed that the production...
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| Veröffentlicht in: | J Phys Chem Lett |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293176/ https://ncbi.nlm.nih.gov/pubmed/27525349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.6b01624 |
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