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Specific Binding of Cholesterol to C99 Domain of Amyloid Precursor Protein Depends Critically on Charge State of Protein

Recent NMR chemical shift measurements of the 99 residue C-terminal fragment of Amyloid Precursor Protein (APP-C99) in the presence of cholesterol provide evidence of binary complex formation between C99 and cholesterol in membrane mimetic environments. It has also been observed that the production...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Phys Chem Lett
Prif Awduron: Panahi, Afra, Bandara, Asanga, Pantelopulos, George A., Dominguez, Laura, Straub, John E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293176/
https://ncbi.nlm.nih.gov/pubmed/27525349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.6b01624
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