Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism

Cholesterol is important for normal brain function. The brain synthesizes its own cholesterol, presumably in astrocytes. We have previously shown that diabetes results in decreased brain cholesterol synthesis by a reduction in sterol regulatory element-binding protein 2 (SREBP2)-regulated transcript...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ferris, Heather A., Perry, Rachel J., Moreira, Gabriela V., Shulman, Gerald I., Horton, Jay D., Kahn, C. Ronald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293102/
https://ncbi.nlm.nih.gov/pubmed/28096339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620506114
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak