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Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications
Macrophage activation is a critical step in host responses during bacterial infections. Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine metabolism, has been well studied in epithelial cells and is known to have essential roles in many different cellular functions. However, its r...
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發表在: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
National Academy of Sciences
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293075/ https://ncbi.nlm.nih.gov/pubmed/28096401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614958114 |
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