Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications

Macrophage activation is a critical step in host responses during bacterial infections. Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine metabolism, has been well studied in epithelial cells and is known to have essential roles in many different cellular functions. However, its r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hardbower, Dana M., Asim, Mohammad, Luis, Paula B., Singh, Kshipra, Barry, Daniel P., Yang, Chunying, Steeves, Meredith A., Cleveland, John L., Schneider, Claus, Piazuelo, M. Blanca, Gobert, Alain P., Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293075/
https://ncbi.nlm.nih.gov/pubmed/28096401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614958114
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