Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity

Mitochondrial fusion is thought to be important for supporting cardiac contractility, but is hardly detectable in cultured cardiomyocytes and is difficult to directly evaluate in the heart. We overcame this obstacle through in vivo adenoviral transduction with matrix-targeted photoactivatable GFP an...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Eisner, Verónica, Cupo, Ryan R., Gao, Erhe, Csordás, György, Slovinsky, William S., Paillard, Melanie, Cheng, Lan, Ibetti, Jessica, Chen, S. R. Wayne, Chuprun, J. Kurt, Hoek, Jan B., Koch, Walter J., Hajnóczky, György
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293028/
https://ncbi.nlm.nih.gov/pubmed/28096338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617288114
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