COX2/mPGES1/PGE(2) pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

In recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)–mediated inhibition of activated PD-1(+) T lymphocytes plays a major role in tumor escape from immune system during cancer progression. Lately, the anti–PD-L1 and –PD-1 immune therapies have become an import...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Prima, Victor, Kaliberova, Lyudmila N., Kaliberov, Sergey, Curiel, David T., Kusmartsev, Sergei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293015/
https://ncbi.nlm.nih.gov/pubmed/28096371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612920114
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