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Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

Reprogramming of human somatic cells into induced pluripotent stem (iPS) cells has greatly expanded the set of research tools available to investigate the molecular and cellular mechanisms underlying central nervous system (CNS) disorders. Reali zing the promise of iPS cell technology for the identi...

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Bibliographic Details
Published in:Curr Protoc Hum Genet
Main Authors: Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293008/
https://ncbi.nlm.nih.gov/pubmed/28075486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphg.33
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