In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer

Therapeutic monoclonal antibodies against the epidermal growth factor receptor (EGFR) act by inhibiting EGFR downstream signaling and by eliciting a natural killer (NK) cell-mediated antitumor response. The IgG(1) mAb cetuximab has been used for treatment of RAS(wt) metastatic colorectal cancer (mCR...

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Vydáno v:Front Immunol
Hlavní autoři: Veluchamy, John P., Lopez-Lastra, Silvia, Spanholtz, Jan, Bohme, Fenna, Kok, Nina, Heideman, Daniëlle A. M., Verheul, Henk M. W., Di Santo, James P., de Gruijl, Tanja D., van der Vliet, Hans J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292674/
https://ncbi.nlm.nih.gov/pubmed/28220124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00087
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