Oncostatin M Suppresses Activation of IL-17/Th17 via SOCS3 Regulation in CD4(+) T Cells

Oncostatin M (OSM) is a pleiotropic cytokine and a member of the IL-6 family. It has both proinflammatory and anti-inflammatory functions and is involved in the activation of STAT3 and STAT5. Rheumatoid arthritis is an autoimmune disease that causes chronic and excessive inflammation. Rheumatoid art...

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Bibliographic Details
Published in:J Immunol
Main Authors: Son, Hye-Jin, Lee, Seung Hoon, Lee, Seon-Yeong, Kim, Eun-Kyung, Yang, Eun-Ji, Kim, Jae-Kyung, Seo, Hyeon-Beom, Park, Sung-Hwan, Cho, Mi-La
Format: Artigo
Language:Inglês
Published: AAI 2017
Subjects:
Immune Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292586/
https://ncbi.nlm.nih.gov/pubmed/28093521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502314
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