Pharmacodynamic Profiling of Piperacillin in the Presence of Tazobactam in Patients through the Use of Population Pharmacokinetic Models and Monte Carlo Simulation

The primary objectives of this analysis were to determine which pharmacokinetic model most accurately describes the elimination pathways for piperacillin in the presence of tazobactam through population pharmacokinetic modeling and to characterize its pharmacodynamic profile. Once the optimal pharma...

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Bibliographic Details
Main Authors: Lodise, Thomas P., Lomaestro, Ben, Rodvold, Keith A., Danziger, Larry H., Drusano, George L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC529233/
https://ncbi.nlm.nih.gov/pubmed/15561849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4718-4724.2004
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