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Curcumin Suppresses Intestinal Fibrosis by Inhibition of PPARγ-Mediated Epithelial-Mesenchymal Transition

Intestinal fibrotic stricture is a major complication of Crohn's disease (CD) and epithelial-to-mesenchymal transition (EMT) is considered as an important contributor to the formation of intestinal fibrosis by increasing extracellular matrix (ECM) proteins. Curcumin, a compound derived from rhi...

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Bibliographic Details
Published in:Evid Based Complement Alternat Med
Main Authors: Xu, Su, Jiang, Bin, Wang, Hui, Shen, Cunsi, Chen, Hao, Zeng, Li
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292200/
https://ncbi.nlm.nih.gov/pubmed/28203261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7876064
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